Bioactive Signalling in Stem Cell Skincare
Stem Cell Skincare does not typically contain live cells; rather, it utilizes "Secretomes" or "Exosomes" derived from plant or human-conditioned media to trigger cellular repair.
1. Culturing and Conditioned Media
Stem cells (often from Swiss Apples or Centella Asiatica) are grown in a bioreactor. During their growth cycle, they secrete Growth Factors, cytokines, and signal peptides into the surrounding liquid (conditioned media). This media is then filtered and concentrated for topical application.
2. Exosome Delivery Systems
The technical efficacy of these products relies on delivery. Exosomes are lipid-bilayer vesicles that act as "shuttles" for genetic information and proteins. Because of their lipophilic nature, they can penetrate the stratum corneum more effectively than raw proteins, delivering signals directly to the fibroblasts in the dermis.
3. Synthesis of Type I Collagen
The primary biochemical objective is the stimulation of Neocollagenesis. The peptides found in stem cell extracts act as ligands that bind to cell surface receptors, "signalling" the skin to increase the production of collagen and elastin, thereby reinforcing the extracellular matrix.
